C2orf40 inhibits metastasis and regulates chemo-resistance and radio-resistance of nasopharyngeal carcinoma cells by influencing cell cycle and activating the PI3K/AKT/mTOR signaling pathway. (PMID: 35676661) Xie Z … Zhang X (Journal of translational medicine 2024) 3 WebECRG4 INFORMATION. Proteini. Full gene name according to HGNC. ECRG4 augurin precursor. Gene namei. Official gene symbol, which is typically a short form of the gene …
Gene: C2orf40 (ENSG00000119147) - Summary - Homo_sapiens
WebApr 11, 2024 · Since this discovery, several studies have been carried out to better understand the biological functions of augurin. In 2007, Mirabeau and co-workers in the attempt to identify genes encoding peptide hormones in the human genome, described one potential candidate encoded by C2orf40, which lies in the same locus as ECRG4. WebFeb 12, 2024 · In addition, C2orf40 can increase the expression of p21 through interaction with UBR5. Conclusions. Low expression levels of C2orf40 are related to the hypermethylation of its promoter. C2orf40 can inhibit HCC through UBR5-dependent or p53-independent mechanisms. C2orf40 may be a diagnostic biomarker and a potential … military life insurance vgli
The Orphan C2orf40 Gene is a Neuroimmune Factor in
WebFeb 12, 2024 · The recovery of C2orf40 expression in HCC cell lines can induce G0/G1 phase arrest and apoptosis, and also inhibit cell migration and invasion by reversing the … WebShowing 25 of 287 Results for C2orf40 Search Time: 0 ms Showing 25 50 100 200 500 See All of 287 Results for C2orf40 Search Time: 0 ms Export WebDec 15, 2024 · Introduction. In humans, the Esophageal Cancer Related Gene-4 (ECRG4, also called c2orf40) consists of 4 exons that span about 12.6 kb of chromosome 2q12.2 (Baird et al., 2014).Briefly, c2orf40 transcription produces an mRNA encoding a 447 base pair (bp) open reading frame (ORF) that is then translated into a protein called ECRG4, a … military lifestyle and culture