WebNov 4, 2024 · CircPVT1 (hsa_circ_0001821) is a cancer-related circular RNA (circRNA) that originated from a genomic locus on chromosome 8q24. This locus has been … WebApr 3, 2024 · CircPVT1 acts as a competing endogenous RNA (ceRNA) to sponge miR-181a-2-3p, promoting the expression of ESR1 and downstream ERα-target genes and …
The biogenesis, biology and characterization of circular RNAs
WebApr 1, 2024 · CircPVT1, as an oncogenic circRNA, has been found to be upregulated in various human cancers, such as GC, CRC, BCa, and osteosarcoma. 15, 16, 20 It has … WebFeb 16, 2024 · CircPVT1 was over-expressed in OS tissues and cells, and correlated with clinical features of OS. Over-expressed circPVT1 reduced the survival of OS patients. CircPVT1 was up-regulated in chemoresistant OS cells compared to their parental cells. CircPVT1 inhibition suppressed the proliferation and chemoresistance of OS cells. cynthia eckes morgan stanley
CircPVT1 promotes ER-positive breast tumorigenesis and drug …
WebApr 3, 2024 · CircPVT1 acts as a competing endogenous RNA (ceRNA) to sponge miR-181a-2-3p, promoting the expression of ESR1 and downstream ERα-target genes and … WebMay 7, 2024 · Background Medullary thyroid cancer (MTC) represents 13.4 % of all thyroid cancers-related deaths. The treatments for MTC are very limited especially for patients with distal metastasis. Therefore, it is critical to understand the mechanisms of MTC to pursue novel therapeutic avenues. Here, we studied the function of circPVT1/miR-455-5p in … WebOct 15, 2024 · b The circPVT1 was markedly up-regulated in EC tissues compared with the adjacent tissues. **P < 0.01; n = 20. c The level of circPVT1 was significantly increased in cancer cell lines, especially in EC109, TE-1 and TE-10. **P < 0.01; n = 3. d The circPVT1 levels decreased significantly when TE-1 cells were maintained to over-confluence. billy strings concert schedule 2023