WebFeb 1, 2024 · There is a risk of ototoxic effects if cisplatin and Lasix are given concomitantly. In addition, nephrotoxicity of nephrotoxic drugs such as cisplatin may … Webprevention of chemotherapy-induced nausea and vomiting in patients receiving high-dose cisplatin: a multicentre, randomised, double-blind, placebo-controlled phase 3 trial. Ann Oncol. 2013 Apr;24(4):1067–73. 19. Aapro MS, Walko CM. Aprepitant: drug-drug interactions in perspective. Ann Oncol. 2010 Dec;21(12):2316–23. 20.
Lasix: Package Insert / Prescribing Information - Drugs.com
WebTo overcome this problem, we developed a strategy for promoting cisplatin-induced ototoxicity by coadministration of furosemide a loop diuretic. A dose-response study … WebOtotoxic drugs include antibiotics (such as gentamicin, streptomycin, tobramycin ), loop diuretics (such as furosemide ), and platinum -based chemotherapy agents (such as cisplatin and carboplatin ). A number of nonsteroidal anti-inflammatory drugs (NSAIDS) have also been shown to be ototoxic. notify thread
Nephrotoxicity as a Dose-Limiting Factor in a High-Dose Cisplatin …
WebFeb 17, 2024 · Cisplatin. There is a risk of ototoxic effects if cisplatin and furosemide are given concomitantly [see Warnings and Precautions (5.3)]. Cisplatin and nephrotoxic drugs. Nephrotoxicity. Administer furosemide at lower doses and with postitive fluid balance when used to achieve forced diuresis during cisplatin treatment. Monitor renal function. WebThe primary objective for this study was to determine whether mannitol or furosemide provides better nephroprotection when administered with hydration prior to weekly, low-dose cisplatin concurrently with whole pelvic radiotherapy. Methods: Creatinine clearance was estimated using the IDMS-traceable MDRD Study Equation. WebFeb 25, 2024 · Uses for Lasix Furosemide belongs to a group of medicines called loop diuretics (also known as water pills). Furosemide is given to help treat fluid retention (edema) and swelling that is caused by congestive heart failure, liver disease, kidney disease, or other medical conditions. It works by acting on the kidneys to increase the … notify the federal government of a death