WebCynomolgus BAFF/BLyS HEK293 Cells Overexpression Lysate 90267-C01HL is validated in western blot (WB) as positive control. Sino Biological offers bulk order for high quality … WebFeb 1, 2006 · BAFF has three receptors on B cells, the most crucial of which is BR3. In this study, we demonstrate the biological outcome of BAFF blockade in cynomolgus monkeys using a soluble fusion protein consisting of human BR3 and human IgG1 Fc. In vitro, BR3-Fc blocked BAFF-mediated survival and proliferation of cynomolgus monkey B cells. …
A Soluble BAFF Antagonist, BR3-Fc, Decreases Peripheral
WebApr 6, 2024 · It was selected based on potent T cell activation and anti-MM activity in preclinical models with favorable tolerability in cynomolgus monkey. In the ongoing first-in-human phase I... WebMolecule Mass: Therecombinant cynomolgus TNFSF13B is a disulfide-linked homodimer. reduced monomer comprises 412 amino acids and has a calculated molecular mass of 45.5 KDa.The apparent molecular mass of the protein is approximately 47 KDa respectively in SDS-PAGE. Species: Cynomolgus BAFF/BLyS Transfected / Overexpression Cell … iro hero trophy guide
Full article: Development of tibulizumab, a tetravalent bispecific ...
WebImmobilized Cynomolgus BAFF/BLyS hFc (Cat:90267-C01H) at 2 μg/mL (100 μL/well) can bind Rhesus BCMA (hFc & AVI Tag), Biotinylated (Cat:90103-C35H-B), the EC 50 is 15-80 ng/mL. Protein Construction A DNA sequence encoding the rhesus TNFRSF17 (XP_001106892.1) (Met1-Ala53) was expressed with a c-terminal AVI tagged Fc region … WebRecombinant-Cynomolgus BAFF/TNFSF13B/CD257 Trimer-N-His-Avi, N-Flag protein was developed from hek293 and has a target region of N-His-Avi, N-Flag. For use in research … WebTabalumab, a human IgG4 monoclonal antibody (mAb) with neutralizing activity against both soluble and membrane B-cell activating factor (BAFF), has been under development for the treatment of autoimmune diseases. iro high orc